Molino D, Perrotti P, Antropoli C, Bottino V, Napoli V, Fioretto R
Divisione VII, Chirurgia Gastroenterologica Azienda Ospedaliera di Rilievo Nazionale A. Cardarelli, Napoli.
Chir Ital. 2001 May-Jun;53(3):319-25.
We report our experience with middle segment pancreatectomy for benign, cystic and borderline tumours of the neck and body of the pancreas. The guidelines for management of these tumours are unclear. Formerly they were usually resected with a pancreatico-duodenectomy or distal pancreatectomy including the spleen. However, such operations may cause high morbidity, a notable wastage of normal tissue and an unnecessary risk of diabetes mellitus and splenic loss. Four patients (age range: 34-72 years) with tumours of the neck or body of the pancreas underwent a middle segmental pancreatectomy. The cephalic stump was sutured with duct ligation. The distal stump was anastomosed with a Roux-en-Y jejunal loop. Neither pancreatic fistulas nor operative death occurred in any of the patients. In 3 patients with serous cystadenoma and in one with mucinous cystadenoma, the tumours measured 3.5 to 7 cm in size. These were located in the neck and body of the pancreas and could not be safely enucleated without compromising the pancreatic duct. All tumours were resected with clear margins. The mean operative time was 230 minutes and the median postoperative hospital stay 14 days (range: 10-23 days). The patients have been followed up for five years after surgery and all are disease-free. None of the patients became diabetic or presented exocrine insufficiency. Middle segment pancreatectomy may be an appropriate technique for selected benign or borderline pancreatic tumours in the neck and body of the pancreas. This procedure has an acceptable surgical risk when compared to that of major pancreatic resections and preserves pancreatic function and the spleen.
我们报告了对胰腺颈部和体部的良性、囊性及交界性肿瘤行中段胰腺切除术的经验。这些肿瘤的治疗指南尚不明确。以前,它们通常采用胰十二指肠切除术或包括脾脏的远端胰腺切除术进行切除。然而,此类手术可能导致高发病率、正常组织的大量浪费以及糖尿病和脾脏丢失的不必要风险。4例(年龄范围:34 - 72岁)胰腺颈部或体部肿瘤患者接受了中段胰腺切除术。胰头残端采用导管结扎缝合。远端残端与Roux - en - Y空肠袢吻合。所有患者均未发生胰瘘或手术死亡。3例浆液性囊腺瘤患者和1例黏液性囊腺瘤患者的肿瘤大小为3.5至7厘米。这些肿瘤位于胰腺颈部和体部,若不损伤胰管则无法安全地摘除。所有肿瘤均切除边缘清晰。平均手术时间为230分钟,术后中位住院时间为14天(范围:10 - 23天)。患者术后已随访5年,均无疾病复发。所有患者均未患糖尿病或出现外分泌功能不全。中段胰腺切除术对于胰腺颈部和体部某些选定的良性或交界性胰腺肿瘤可能是一种合适的技术。与主要的胰腺切除术相比,该手术具有可接受的手术风险,并能保留胰腺功能和脾脏。