Macrì A, Scuderi G, Saladino E, Trimarchi G, Terranova M, Versaci A, Famulari C
Emergency Surgery Unit, University of Messina, Messina 98125, Italy.
Surg Endosc. 2006 Jan;20(1):88-91. doi: 10.1007/s00464-005-0178-6. Epub 2005 Dec 7.
The treatment of acute cholecystitis in the elderly is still a subject of debate, particularly with reference to the timing of surgery and the role of laparoscopy.
From January 1994 to June 2002 we observed 27 patients aged over 70 years with acute calcolous cholecystitis. The patients were submitted to ultrasonographic percutaneous cholecystostomy within 12 h of the acute attack. For two patients (7.4%) at high operative risk, we chose a conservative treatment. Twenty-five patients (92.6%) were submitted, in 15 cases (60%) within 5 days and in 10 patients (40%) within 8 days, to a laparoscopic cholecystectomy. Statistical significance was accepted when the value of p was less than 0.05.
Ultrasonographic percutaneous cholecystostomy was performed successfully in all patients, without major morbidity or mortality, and complete resolution of clinical symptoms was obtained within 48 h. The conversion rate of laparoscopy was 20% (13.3% in patients submitted to surgery within 5 days and 30% in the group submitted within 8 days--p > 0.05). The postoperative morbidity rate was 24%; it was higher (40% versus 15%) in patients converted to laparotomy (p > 0.05); mortality was 4%. The period of hospitalization was 11 days in patients operated laparoscopically and 21 days in those converted to open cholecystectomy (p < 0.001).
The more rational treatment of acute calcolous cholecystitis in elderly patients is represented by ultrasonographic percutaneous cholecystostomy followed, within 5 days, by laparoscopic cholecystectomy using an abdominal insufflation maximum to 12 mmHg and a limited 10-15 degrees head-up tilt.
老年人急性胆囊炎的治疗仍是一个有争议的话题,特别是在手术时机和腹腔镜检查的作用方面。
1994年1月至2002年6月,我们观察了27例年龄超过70岁的急性结石性胆囊炎患者。这些患者在急性发作后12小时内接受了超声引导下经皮胆囊造瘘术。对于两名手术风险高的患者(7.4%),我们选择了保守治疗。25例患者(92.6%)接受了腹腔镜胆囊切除术,其中15例(60%)在5天内进行,10例(40%)在8天内进行。当p值小于0.05时,认为具有统计学意义。
所有患者超声引导下经皮胆囊造瘘术均成功实施,无严重并发症或死亡,48小时内临床症状完全缓解。腹腔镜检查的转换率为20%(5天内接受手术的患者为13.3%,8天内接受手术的组为30%——p>0.05)。术后发病率为24%;转为剖腹手术的患者发病率更高(40%对15%)(p>0.05);死亡率为4%。腹腔镜手术患者的住院时间为11天,转为开腹胆囊切除术的患者为21天(p<0.001)。
老年患者急性结石性胆囊炎更合理的治疗方法是先进行超声引导下经皮胆囊造瘘术,然后在5天内进行腹腔镜胆囊切除术,腹腔内充气最大至12mmHg,头高脚低倾斜10 - 15度。