老年患者经皮胆囊造瘘术的结局：一项系统评价和荟萃分析。
Outcomes of percutaneous cholecystostomy in elderly patients: a systematic review and meta-analysis.
作者信息
Markopoulos George, Mulita Francesk, Kehagias Dimitris, Tsochatzis Stylianos, Lampropoulos Charalampos, Kehagias Ioannis
机构信息
Department of Surgery, General University Hospital of Patras, Patras, Greece.
出版信息
Prz Gastroenterol. 2021;16(3):188-195. doi: 10.5114/pg.2020.100658. Epub 2020 Nov 5.
INTRODUCTION
Percutaneous cholecystostomy (PC) represents a management option to control sepsis in patients with acute cholecystitis, who are unable to tolerate surgery.
AIM
This review aimed to evaluate the outcomes of elderly patients treated with PC and compare it with emergent cholecystectomy.
MATERIAL AND METHODS
An electronic search of the Embase, Medline Web of Science, and Cochrane databases was performed. Percutaneous cholecystostomy was used as the reference group, and weighted mean differences (WMD) were calculated for the effect of PC on continuous variables, and pooled odds ratios (POR) were calculated for discrete variables.
RESULTS
There were 20 trials included in this review. Utilisation of PC was associated with significantly increased mortality (POR = 4.85; 95% CI: 1.02-7.30; = 0.0001) and increased re-admission rates (POR = 2.95; 95% CI: 2.21-3.87; < 0.0001).
CONCLUSIONS
This pooled analysis established that patients treated with PC appear to have increased mortality and readmission rates relative to those managed with cholecystectomy.
引言
经皮胆囊造瘘术（PC）是一种用于治疗无法耐受手术的急性胆囊炎患者以控制感染的治疗选择。
目的
本综述旨在评估接受PC治疗的老年患者的治疗结果，并将其与急诊胆囊切除术进行比较。
材料与方法
对Embase、Medline科学网和Cochrane数据库进行了电子检索。以经皮胆囊造瘘术作为参照组，计算PC对连续变量影响的加权平均差（WMD），并计算离散变量的合并比值比（POR）。
结果
本综述纳入了20项试验。使用PC与死亡率显著增加（POR = 4.85；95%置信区间：1.02 - 7.30；P = 0.0001）和再入院率增加（POR = 2.95；95%置信区间：2.21 - 3.87；P < 0.0001）相关。
结论
这项汇总分析表明，与接受胆囊切除术治疗的患者相比，接受PC治疗的患者死亡率和再入院率似乎有所增加。
Zotero 插件