Schaumann Anselm, Gödde Martin, Tönnis Tobias
Abteilung Kardiologie, AK St. Georg, Hamburg,
Herz. 2005 Nov;30(7):591-5. doi: 10.1007/s00059-005-2753-y.
In addition to secondary prevention of sudden cardiac death (SCD), the number of cardioverter defibrillator implantations (ICD) for primary prevention is increasing. An indication for primary prevention of SCD is supported by results of the MADIT II, Companion and SCD-HeFT trials. The main risk factor for SCD is the reduced left ventricular function (LVEF < or = 35%). For selecting the appropriate ICD device and the number of leads, several clinical parameters are important. For the primary prevention of SCD a single-lead VVI ICD is usually sufficient. In case of AV conduction delay and symptomatic heart failure with a prolonged QRS duration a biventricular ICD device is preferred in favor of a ventricular resynchronization. The use of a dual-chamber device should be limited to sinus nodal disease and better discrimination capabilities for slow ventricular tachycardias.
除了心脏性猝死(SCD)的二级预防外,用于一级预防的心脏复律除颤器植入术(ICD)的数量也在增加。MADIT II、Companion和SCD-HeFT试验的结果支持了SCD一级预防的指征。SCD的主要危险因素是左心室功能降低(左心室射血分数LVEF≤35%)。为选择合适的ICD装置和导联数量,几个临床参数很重要。对于SCD的一级预防,单腔VVI ICD通常就足够了。如果存在房室传导延迟和伴有QRS波时限延长的症状性心力衰竭,双心室ICD装置因有利于心室再同步化而更受青睐。双腔装置的使用应限于窦房结疾病以及对缓慢室性心动过速有更好的鉴别能力的情况。