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钙化上皮性牙源性肿瘤的细胞学表现:一例报告

Cytologic findings in calcifying epithelial odontogenic tumor: a case report.

作者信息

Shekarkhar Mohammad Javad, Tabei Seyed Z, Kumar Perikala V, Hashemi Seyed Baseer

机构信息

Department of Pathology and Otolaryngology, Shiraz Medical School, Shiraz University of Medical Sciences, Islamic Republic of Iran.

出版信息

Acta Cytol. 2005 Sep-Oct;49(5):533-6. doi: 10.1159/000326201.

Abstract

BACKGROUND

Calcifying epithelial odontogenic tumor (CEOT), or Pindborg's tumor, is a rare, benign, odontogenic neoplasm first described by Pindborg in 1955. It is most commonly seen in the fourth and fifth decades of life, usually arises in the mandibular premolar-molar areas and accounts for approximately 1% of all intraosseous odontogenic tumors. This report describes the cytologic findings in a case of CEOT.

CASE

A 62-year-old woman was referred to the ear, nose and throat clinic with a right maxillary mass. The fine needle aspiration (FNA) smears showed numerous calcifications; amorphous, eosinophilic material; and clusters of round epithelial cells embedded in a bloody background. The smears were diagnosed as suspicious for malignancy. Maxillectomy was done. The histologic sections were diagnosed as CEOT.

CONCLUSION

FNA findings of calcifying epithelial odontogenic tumor have been described rarely. The clusters of epithelial cells with prominent nucleoli are mistaken for features of a malignant tumor.

摘要

背景

钙化上皮性牙源性肿瘤(CEOT),即平博氏瘤,是一种罕见的良性牙源性肿瘤,1955年由平博首次描述。它最常见于40至50岁人群,通常发生在下颌前磨牙-磨牙区,约占所有骨内牙源性肿瘤的1%。本报告描述了一例CEOT的细胞学检查结果。

病例

一名62岁女性因右侧上颌肿物被转诊至耳鼻喉科门诊。细针穿刺(FNA)涂片显示大量钙化;无定形嗜酸性物质;以及嵌入血性背景中的圆形上皮细胞簇。涂片诊断为可疑恶性肿瘤。行上颌骨切除术。组织学切片诊断为CEOT。

结论

钙化上皮性牙源性肿瘤的FNA检查结果鲜有报道。具有明显核仁的上皮细胞簇易被误认为是恶性肿瘤的特征。

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