Fulciniti F, Vetrani A, Zeppa P, Califano L, Palombini L
Cytopathology Laboratory and Service, Faculty of Medicine and Surgery, University of Naples Federico II, Italy.
Diagn Cytopathol. 1995 Feb;12(1):71-5. doi: 10.1002/dc.2840120117.
A 44-yr-old woman with a long-standing history of painful mandibular swelling was hospitalized for the diagnostic evaluation of an osteolytic mandibular lesion in the premolar-canine area. Fine-needle aspiration biopsy (FNAB) was performed and cytologic smears were characterized by clusters, sheets, and rare isolated pleomorphic cells of the squamoid type, blocks of amorphous material encircled by fibroblasts, and occasional calcifications. A cytological diagnosis of Pindborg's tumor was made, which was confirmed by histopathological examination. Evaluation of DNA ploidy by semiautomated image cytometry produced an aneuploid histogram. The patient is free of residual neoplasm at a 12-mo post-operative interval. The cytological differential diagnosis of this rare odontogenic neoplasm is discussed briefly.
一名有长期下颌疼痛肿胀病史的44岁女性因前磨牙-尖牙区溶骨性下颌骨病变的诊断评估而住院。进行了细针穿刺活检（FNAB），细胞学涂片的特征为鳞状细胞样的细胞团、细胞片和罕见的孤立多形性细胞、被成纤维细胞围绕的无定形物质块以及偶尔的钙化。做出了平博氏瘤的细胞学诊断，该诊断经组织病理学检查得以证实。通过半自动图像细胞术评估DNA倍性产生了非整倍体直方图。术后12个月时患者无残留肿瘤。本文简要讨论了这种罕见牙源性肿瘤的细胞学鉴别诊断。
