基于葡聚糖的水凝胶及其药物控释的应用研究
[Application research on dextran-based hydrogel and its drug controlled release].
作者信息
Chen Faming, Wu Zhifen, Jin Yan
机构信息
Center Laboratory for Tissue Engineering, College of Stomatology, the Fourth Military Medical University, Xi'an Shaanxi, 710032, P. R. China.
出版信息
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2005 Nov;19(11):919-22.
OBJECTIVE
To introduce the development of dextran-based hydrogel and its drug delivery system in drug sustained and/or controlled release, and to investigate their application in tissue engineering.
METHODS
Related literature was extensively reviewed and comprehensively analyzed.
RESULTS
In recent years, great progress was made in the studies of dextran-based hydrogels and study on dextran-based intelligent materials became an investigative hotspot especially in tissue engineering.
CONCLUSION
Dextran-based hydrogel is considered to be a good potential material in field of drug delivery and tissue engineering. Endowed with new characteristics, a series of intelligent biomaterials can be derived from dextran-based hydrogels, which can be widely used in biomedicine. Further study should be done on the industrialization of its interrelated production.
目的
介绍基于葡聚糖的水凝胶及其药物递送系统在药物缓释和/或控释方面的发展，并研究它们在组织工程中的应用。
方法
广泛查阅并综合分析相关文献。
结果
近年来，基于葡聚糖的水凝胶研究取得了很大进展，基于葡聚糖的智能材料研究成为一个研究热点，尤其是在组织工程领域。
结论
基于葡聚糖的水凝胶被认为是药物递送和组织工程领域具有良好潜力的材料。基于葡聚糖的水凝胶可衍生出一系列具有新特性的智能生物材料，可广泛应用于生物医学领域。应进一步研究其相关生产的产业化问题。
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