Panteris Vasilios, Karamanolis D G
Department of Gastroenterology, Tzaneion General Hospital of Piraeus, Greece.
Hepatogastroenterology. 2005 Nov-Dec;52(66):1782-91.
Functional dyspepsia is still a puzzling medical problem. The causes are unknown, the pathogenetic mechanisms are uncertain, the management is controversial and medications are many times insufficient. The research so far has given conflicting results at all levels of investigation. This study represents an effort to collect all available data concerning the most disputed issues of functional dyspepsia. Topics regarding Helicobacter pylori eradication, pathophysiology, endoscopic and histologic correlations with symptomatology, the placebo effect and management options are presented following an evidence-based approach. Many articles, published in recent years, are discussed in order to obtain an overall insight of this peculiar symptom complex, named functional dyspepsia.
功能性消化不良仍然是一个令人困惑的医学问题。其病因不明，发病机制不确定，治疗存在争议，药物治疗往往效果不佳。迄今为止的研究在各个层面的调查中都给出了相互矛盾的结果。本研究旨在收集所有关于功能性消化不良最具争议问题的现有数据。按照循证医学的方法，介绍了与幽门螺杆菌根除、病理生理学、内镜及组织学与症状学的相关性、安慰剂效应和治疗选择等相关的主题。为了全面了解这种名为功能性消化不良的特殊症状复合体，对近年来发表的许多文章进行了讨论。
