Scherer C
Service de neurologie du Pr Giroud, CHU de Dijon (21).
Presse Med. 2005 Sep 10;34(15):1084-6. doi: 10.1016/s0755-4982(05)84123-5.
In patients older than 50 years, a first seizure can reveal non-ketotic hyperglycemia, regardless of any previous history of diabetes mellitus. Partial motor seizures are observed in most cases, sometimes with epilepsia partialis continua. Plasma glucose levels are usually above 20 mmol/L, and serum osmolarity is normal or slightly elevated. The absence of ketoacidosis may promote the occurrence of seizures. EEG and neuroimaging between seizures are usually normal. Treatment involves correction of the hyperglycemia with insulin treatment and rehydration.
在50岁以上的患者中，首次发作可能提示非酮症高血糖，无论其既往有无糖尿病史。多数情况下会出现部分性运动发作，有时伴有持续性部分性癫痫。血浆葡萄糖水平通常高于20 mmol/L，血清渗透压正常或略有升高。无酮症酸中毒可能促使癫痫发作。发作间期的脑电图和神经影像学检查通常正常。治疗包括用胰岛素治疗纠正高血糖和补液。
