Ocón Bretón J, Pérez Naranjo S, Gimeno Laborda S, Benito Ruesca P, García Hernández R
Servicio de Endocrinología y Nutrición, Unidad de Nutrición, Hospital Clinico Universitario Lozano Blesa, Zaragoza, España.
Nutr Hosp. 2005 Nov-Dec;20(6):409-14.
Bariatric surgery represents an affective therapeutic alternative for patients with morbid obesity refractory to medical treatment. However, these surgical techniques increase the risk of producing a protein-energy hyponutrition or a selective deficit of some micronutrient. The aim of this work has been to analyze the anthropometrical, nutritional, digestive and cardiovascular risk factors changes and quality of life in patients with morbid obesity submitted to bariatric surgery.
Retrospective descriptive study evaluating a group of patients with morbid obesity submitted to bariatric surgery (45 by means of biliopancreatic bypass according to Scopirano's procedure, and 25 by laparoscopic gastric bypass). Anthropometrics (height, weight, body mass index), cardiovascular risk factors (arterial blood pressure, lipid and glycemic profiles, serum uric acid) and nutritional parameters (serum albumin, complete blood count, and phosphorus and calcium) were assessed before the bariatric procedure and one and two years after surgical treatment. Quality of life was evaluated through the B.A.R.O.S. system.
Seventy patients with morbid obesity have been analyzed (56 women and 14 men) with a mean age of 36.5 +/- 11 years. Mean pre-surgical weight was 129.7 +/- 25.6 kg and BMI 48.8 +/- 8.8 kg/m2. Two years after the surgical procedure BMI was 31.0 +/- 6.6 kg/m2, the ponderal reduction 47.7 kg and the percentage of weight loss 36.5%. Hundred percent of dislipidemic patients, 90% of diabetic patients, and 72% of hypertensive patients normalized their corresponding profiles after surgery. The most common nutritional complications were anemia and iron deficiency, which occurred in 54.4% and 36.6% of the cases, respectively. Other observed nutritional deficits were: mild hypoalbuminemia in 20.3% of the patients, hypothrombinemia in 14.9%, folic acid decrease in 17.8%, vitamin B12 deficiency in 12.5%, hypocalcaemia in 23.8%, and secondary hyperparathyroidism in 45.4% of the cases. All nutritional complications were more frequent in patients submitted to biliopancreatic bypass, with the exception for vitamin B12 deficiency that occurred more frequently in patients with gastric bypass. The most frequently observed digestive complication was diarrhea/steatorrhea in 39.1% of the cases. Sixty-four point two percent of the patients considered the surgery outcome as excellent or very good.
In patients with morbid obesity, bariatric surgery is a technique by which a great improvement in anthropometrical parameters, cardiovascular risk factors, and quality of life of patients is achieved, but it associates an important percentage of nutritional complications that we should take into account in order to prevent them.
减肥手术是治疗难治性病态肥胖患者的有效治疗选择。然而,这些手术技术会增加蛋白质 - 能量营养不良或某些微量营养素选择性缺乏的风险。本研究旨在分析接受减肥手术的病态肥胖患者的人体测量学、营养、消化和心血管危险因素变化以及生活质量。
回顾性描述性研究,评估一组接受减肥手术的病态肥胖患者(45例行Scopirano法胆胰转流术,25例行腹腔镜胃旁路术)。在减肥手术前、术后1年和2年评估人体测量学指标(身高、体重、体重指数)、心血管危险因素(动脉血压、血脂和血糖谱、血清尿酸)和营养参数(血清白蛋白、全血细胞计数、磷和钙)。通过B.A.R.O.S.系统评估生活质量。
分析了70例病态肥胖患者(56例女性和14例男性),平均年龄36.5±11岁。术前平均体重为129.7±25.6kg,BMI为48.8±8.8kg/m²。手术后两年,BMI为31.0±6.6kg/m²,体重减轻47.7kg,体重减轻百分比为36.5%。100%的血脂异常患者、90%的糖尿病患者和72%的高血压患者术后相应指标恢复正常。最常见的营养并发症是贫血和缺铁,分别发生在54.4%和36.6%的病例中。其他观察到的营养缺乏包括:20.3%的患者有轻度低白蛋白血症,14.9%有凝血酶原血症,17.8%有叶酸降低,12.5%有维生素B12缺乏,23.8%有低钙血症,45.4%的病例有继发性甲状旁腺功能亢进。除了维生素B12缺乏在胃旁路术患者中更常见外,所有营养并发症在接受胆胰转流术的患者中更频繁。最常观察到的消化并发症是腹泻/脂肪泻,发生率为39.1%。64.2%的患者认为手术结果为优秀或非常好。
对于病态肥胖患者,减肥手术是一种能显著改善患者人体测量学参数、心血管危险因素和生活质量的技术,但它会伴有一定比例的营养并发症,我们应予以重视以预防这些并发症。