Winzenberg T M, Oldenburg B, Frendin S, De Wit L, Jones G
Menzies Research Institute, University of Tasmania, Private Bag 23, Hobart, Tasmania 7001, Australia.
Prev Med. 2006 Jan;42(1):21-6. doi: 10.1016/j.ypmed.2005.11.006. Epub 2005 Dec 5.
To assess whether a lifestyle intervention delivered to mothers might impact on osteoporosis preventive behaviors in their children.
We performed a 2-year randomized controlled trial of individualized bone mineral density feedback with either an osteoporosis information leaflet, or small group education, in a population-based sample of 354 mothers from Southern Tasmania, Australia in 2000-02. Main outcomes were maternal report of calcium intake and physical activity change in their children.
Receiving small group education was associated with mothers' report of increasing children's calcium intake (odds ratio 2.3, 95% confidence interval 1.4, 3.8), as was low t-score feedback (odds ratio 2.0, 95% confidence interval 1.2, 3.3). Mothers who increased their own physical activity were more often reported increasing both physical activity (odds ratio 2.7, 95% confidence interval 1.5, 5.0) and calcium intake in their children (odds ratio 2.2, 95% confidence interval 1.3, 3.7). Mothers who commenced calcium supplements more often reported increasing children's calcium intake (odds ratio 2.6, 95% confidence interval 1.0, 6.7) but not physical activity.
Both bone mineral density feedback and small group education delivered to mothers are effective at inducing maternally reported osteoporosis preventive behavior change in their children. These results require confirmation by studies with objective outcome measures.
评估针对母亲实施的生活方式干预是否会对其子女的骨质疏松预防行为产生影响。
2000年至2002年，我们在澳大利亚塔斯马尼亚岛南部以人群为基础的354名母亲样本中进行了一项为期2年的随机对照试验，给予个性化骨密度反馈，并提供骨质疏松信息手册或小组教育。主要结局是母亲报告其子女钙摄入量和身体活动的变化。
接受小组教育与母亲报告子女钙摄入量增加相关（优势比2.3，95%置信区间1.4, 3.8），低t值反馈也与之相关（优势比2.0，95%置信区间1.2, 3.3）。母亲自身身体活动增加的，更常报告子女身体活动增加（优势比2.7，95%置信区间1.5, 5.0）以及钙摄入量增加（优势比2.2，95%置信区间1.3, 3.7）。开始补充钙剂的母亲更常报告子女钙摄入量增加（优势比2.6，95%置信区间1.0, 6.7），但与子女身体活动增加无关。
给予母亲的骨密度反馈和小组教育在促使母亲报告其子女出现骨质疏松预防行为改变方面均有效。这些结果需要通过具有客观结局指标的研究加以证实。
