Functional identification of orthologous genes encoding pterin recycling activity in Plasmodium falciparum and Toxoplasma gondii.
作者信息
Wang Qi, Hauser Vicia, Read Martin, Wang Ping, Hanson Andrew D, Sims Paul F G, Hyde John E
机构信息
Faculty of Life Sciences, University of Manchester, Jackson's Mill, P.O. Box 88, Manchester M60 1QD, United Kingdom.
出版信息
Mol Biochem Parasitol. 2006 Mar;146(1):109-12. doi: 10.1016/j.molbiopara.2005.11.002. Epub 2005 Nov 28.
Abstract
摘要
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Regulation of differentiation to the infective stage of the protozoan parasite Leishmania major by tetrahydrobiopterin.四氢生物蝶呤对原生动物寄生虫硕大利什曼原虫向感染阶段分化的调控
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Characterization of three genes encoding enzymes of the folate biosynthetic pathway in Plasmodium falciparum.恶性疟原虫中编码叶酸生物合成途径中酶的三个基因的特征分析。
Parasitology. 2001 Jan;122 Pt 1:1-13. doi: 10.1017/s0031182000006946.
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Tetrahydrobiopterin biosynthesis, regeneration and functions.四氢生物蝶呤的生物合成、再生及功能。
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High-resolution structures of the bifunctional enzyme and transcriptional coactivator DCoH and its complex with a product analogue.双功能酶与转录共激活因子DCoH及其与产物类似物复合物的高分辨率结构。
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Pseudomonas aeruginosa possesses homologues of mammalian phenylalanine hydroxylase and 4 alpha-carbinolamine dehydratase/DCoH as part of a three-component gene cluster.铜绿假单胞菌拥有哺乳动物苯丙氨酸羟化酶和4α-甲醇胺脱水酶/DCoH的同源物，作为一个三组分基因簇的一部分。
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