Viglinskaya I V
Institute of Pharmacology, USSR Academy of Medical Sciences, Moscow.
Drug Alcohol Depend. 1992 Jun;30(2):111-5. doi: 10.1016/0376-8716(92)90015-5.
In rats, a complex longitudinal analysis of alcohol intake behaviour and electrophysiological sleep pattern was performed during different periods of stable voluntary alcohol consumption. By the sleep pattern, the existence of alcohol abuse and dependence development could be confirmed. Acute ethanol withdrawal was shown to be the obligatory and necessary element in alcohol abuse and dependence evaluation. The proposed behavioural and sleep pattern models might be used in the search for anti-alcoholic drugs in combination with the study of alcoholic aging processes.
在大鼠中，在稳定的自愿饮酒的不同阶段对酒精摄入行为和电生理睡眠模式进行了复杂的纵向分析。根据睡眠模式，可以确认酒精滥用和依赖发展的存在。急性乙醇戒断被证明是酒精滥用和依赖评估中必不可少的要素。所提出的行为和睡眠模式模型可用于寻找抗酒精药物，并结合对酒精性衰老过程的研究。
