氨基烷基苯砜——一类新型的5-羟色胺7受体配体。
Aminoalkyl phenyl sulfones--a novel series of 5-HT7 receptor ligands.
作者信息
Raubo Piotr, Beer Margaret S, Hunt Peter A, Huscroft Ian T, London Clare, Stanton Josephine A, Kulagowski Janusz J
机构信息
The Neuroscience Research Centre, Merck Sharp and Dohme Research Laboratories, Terlings Park, Harlow, Essex CM20 2QR, UK.
出版信息
Bioorg Med Chem Lett. 2006 Mar 1;16(5):1255-8. doi: 10.1016/j.bmcl.2005.11.067. Epub 2005 Dec 7.
PMID:16337790
Abstract
A novel series of 5-HT(7) receptor ligands has been identified and evaluated, providing compounds showing a broad spectrum of functional activities and good selectivity over selected receptors and ion channels.
摘要
已鉴定并评估了一系列新型的5-HT(7)受体配体，得到了对特定受体和离子通道具有广泛功能活性和良好选择性的化合物。
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