Reyes José C
Instituto de Bioquímica Vegetal y Fotosíntesis, Consejo Superior de Investigaciones Científicas, Universidad de Sevilla, Américo Vespucio s/n, E-41092 Sevilla, Spain.
Curr Opin Plant Biol. 2006 Feb;9(1):21-7. doi: 10.1016/j.pbi.2005.11.010. Epub 2005 Dec 7.
The different cell types of a multicellular organism express different sets of genes. Although this is one of the oldest paradigms of developmental genetics, how different patterns of gene expression are established and maintained during subsequent cell division is an active topic of research. Chromatin modifiers play an essential role in controlling gene expression and in establishing epigenetic marks that can be inherited. During the past few years, large number of putative chromatin-associated proteins have been uncovered as controllers of meristem organization and activity, phase transition, and gametophyte and embryo development.
多细胞生物体的不同细胞类型表达不同的基因集。尽管这是发育遗传学最古老的范例之一，但在随后的细胞分裂过程中如何建立和维持不同的基因表达模式仍是一个活跃的研究课题。染色质修饰因子在控制基因表达和建立可遗传的表观遗传标记方面发挥着重要作用。在过去几年中，大量假定的染色质相关蛋白已被发现是分生组织组织和活性、阶段转变以及配子体和胚胎发育的调控因子。
