Meagher Richard B, Kandasamy Muthugapatti K, Deal Roger B, McKinney Elizabeth C
Department of Genetics, University of Georgia, Athens, GA 30602, USA.
Trends Cell Biol. 2007 Jul;17(7):325-32. doi: 10.1016/j.tcb.2007.06.001. Epub 2007 Jul 20.
Regulating developmental transitions, cell proliferation and cell death through differential gene expression is essential to the ontogeny of all multicellular organisms. Chromatin remodeling is an active process that is necessary for managing the genome-wide suppression of gene activities resulting from DNA compaction. Recent data in plants suggest a general theme, whereby chromatin remodeling complexes containing nuclear actin-related proteins (ARPs) potentiate the activities of crucial regulatory genes involved in plant growth and development, in addition to their basal activities on a much larger set of genes.
通过差异基因表达来调控发育转变、细胞增殖和细胞死亡对于所有多细胞生物的个体发育至关重要。染色质重塑是一个活跃的过程，对于管理因DNA压缩导致的全基因组基因活性抑制是必要的。植物中的最新数据表明了一个普遍的主题，即含有核肌动蛋白相关蛋白（ARP）的染色质重塑复合物除了对大量基因具有基础活性外，还增强了参与植物生长和发育的关键调控基因的活性。
