Harms H M, Prank K, Brosa U, Schlinke E, Neubauer O, Brabant G, Hesch R D
Abteilung Klinische Endokrinologie, Medizinische Hochschule Hannover, Germany.
Eur J Clin Invest. 1992 Jun;22(6):371-7. doi: 10.1111/j.1365-2362.1992.tb01476.x.
The biological importance of dynamic hormonal secretion has been demonstrated. There is good evidence from recent studies that parathyroid hormone (PTH) which plays an important role in bone physiology is secreted in a pulsatile manner. In this study we performed a classification of two 'dynamical diseases' namely osteoporosis and hyperparathyroidism by the visualization of dynamic PTH-secretion in multidimensional phase spaces.
动态激素分泌的生物学重要性已得到证实。最近的研究提供了充分的证据，表明在骨骼生理学中起重要作用的甲状旁腺激素（PTH）是以脉冲方式分泌的。在本研究中，我们通过在多维相空间中可视化动态PTH分泌，对两种“动态疾病”即骨质疏松症和甲状旁腺功能亢进症进行了分类。
