Kobayashi Eliane, Thomas Pierre, Andermann Frederick
Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada.
Epileptic Disord. 2005 Dec;7(4):327-31.
Tonic status epilepticus (TSE) in patients with idiopathic generalized epilepsy (IGE) is not well recognized. The objective of this study is to report episodes of TSE in patients with IGE.
We retrospectively reviewed the clinical and EEG evaluation of three IGE patients who presented TSE.
The three patients had mainly clinical features of IGE, but had developed, in addition, focal discharges, diffuse EEG abnormalities and some focal or diffuse neuropsychological dysfunction. The tonic attacks eventually responded to treatment, but were not completely controlled in any of the patients.
The continuum between IGE and secondary generalized epilepsy is demonstrated in these patients. Most of their clinical and EEG features are however, in keeping with an idiopathic generalized epileptic process with additional focal and diffuse components. Recognition of the significance of TSE in such patients has important therapeutic and prognostic implications. [Published with video sequences].
特发性全身性癫痫（IGE）患者的强直性癫痫持续状态（TSE）尚未得到充分认识。本研究的目的是报告IGE患者的TSE发作情况。
我们回顾性分析了3例出现TSE的IGE患者的临床和脑电图评估结果。
这3例患者主要具有IGE的临床特征，但此外还出现了局灶性放电、脑电图弥漫性异常以及一些局灶性或弥漫性神经心理功能障碍。强直性发作最终对治疗有反应，但在任何患者中均未完全得到控制。
这些患者显示出IGE与继发性全身性癫痫之间的连续性。然而，他们的大多数临床和脑电图特征与具有额外局灶性和弥漫性成分的特发性全身性癫痫过程相符。认识到TSE在此类患者中的重要性具有重要的治疗和预后意义。[随视频序列发表]
