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家畜基因组学的进展:打开畜舍之门。

Advances in livestock genomics: opening the barn door.

作者信息

Womack James E

机构信息

Department of Veterinary Pathobiology, Center for Animal Biotechnology and Genomics, Texas A&M University, College Station, Texas 77843-4467, USA.

出版信息

Genome Res. 2005 Dec;15(12):1699-705. doi: 10.1101/gr.3809105.

Abstract

Genome research in animals used in agriculture has progressed rapidly in recent years, moving from rudimentary genome maps to trait maps to gene discovery. These advances are the result of animal genome projects following closely in the footsteps of the Human Genome Project, which has opened the door to genome research in farm animals. In return, genome research in livestock species is contributing to our understanding of chromosome evolution and to informing the human genome. Enhancement of these contributions plus the much anticipated application of DNA-based tools to animal health and production can be expected as livestock genomics enters its sequencing era.

摘要

近年来,用于农业的动物基因组研究进展迅速,从最初的基因组图谱发展到性状图谱,再到基因发现。这些进展是动物基因组计划紧跟人类基因组计划步伐的结果,人类基因组计划为家畜基因组研究打开了大门。反过来,家畜物种的基因组研究有助于我们理解染色体进化,并为人类基因组研究提供信息。随着家畜基因组学进入测序时代,可以预期这些贡献将得到加强,以及基于DNA的工具在动物健康和生产方面的应用备受期待。

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