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超重和肥胖患者的睡眠研究。

Sleep study in patients with overweight and obesity.

作者信息

Namysłowski G, Scierski W, Mrówka-Kata K, Kawecka I, Kawecki D, Czecior E

机构信息

Department of Otolaryngology, Zabrze, Medical University of Silesia, Katowice, Poland.

出版信息

J Physiol Pharmacol. 2005 Dec;56 Suppl 6:59-65.

Abstract

Obstructive sleep apnea syndrome (OSAS) is a disorder characterized by repetitive collapse of the pharyngeal airway during sleep, which leads to oxygen desaturation, sleep fragmentation and daytime somnolence. Obesity is one of the most important risk factor for the development of OSAS. The exact mechanisms responsible for the relationship between obesity and OSAS are still unclear. The fat deposits in the pharynx region as well as the reduction in the lung volume have been considered as factors that might be responsible for the increase of the upper airway collapsibility. The aim of our study was to evaluate the correlation between the Body Mass Index (BMI) and sleep study parameters in overweight and obese patients suffering from breathing disturbances during sleep. We studied a group of 106 consecutive obese or overweight patients with a primary complaint of snoring or other breathing disturbances during sleep. In all cases, BMI and sleep studies (PolyMESAM) were examined. We evaluated relationship between the BMI and sleep study parameters such as Respiratory Disturbance Index (RDI), Apnea Index (AI), Desaturation Index (DI) and Average of Lowest Saturation (LSAT). The results showed the lack of significant statistical correlations between BMI and all the sleep parameters studied in the overweight patients and the statistical positive correlation between the BMI and RDI in the obese cases. We conclude that BMI determination may be considered as a simple, yet important predictor, of the OSAS in the group of obese patients.

摘要

阻塞性睡眠呼吸暂停综合征(OSAS)是一种以睡眠期间咽部气道反复塌陷为特征的疾病,这会导致氧饱和度下降、睡眠片段化和日间嗜睡。肥胖是OSAS发生发展的最重要危险因素之一。肥胖与OSAS之间关系的确切机制仍不清楚。咽部区域的脂肪堆积以及肺容积的减少被认为可能是导致上气道可塌陷性增加的因素。我们研究的目的是评估体重指数(BMI)与睡眠期间存在呼吸障碍的超重和肥胖患者的睡眠研究参数之间的相关性。我们研究了一组106例连续的肥胖或超重患者,他们的主要诉求是打鼾或睡眠期间的其他呼吸障碍。在所有病例中,均检查了BMI和睡眠研究(多导睡眠监测)。我们评估了BMI与睡眠研究参数之间的关系,如呼吸紊乱指数(RDI)、呼吸暂停指数(AI)、去饱和指数(DI)和最低饱和度平均值(LSAT)。结果显示,超重患者的BMI与所有研究的睡眠参数之间缺乏显著的统计学相关性,而在肥胖病例中,BMI与RDI之间存在统计学正相关。我们得出结论,在肥胖患者群体中,BMI测定可被视为OSAS的一个简单但重要的预测指标。

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