第三脑室的胶样囊肿：一项免疫组织化学研究

Colloid cysts of the third ventricle: an immunohistochemical study.

作者信息

Kuchelmeister K, Bergmann M

机构信息

Institute of Neuropathology, University of Münster, Germany.

出版信息

Histopathology. 1992 Jul;21(1):35-42. doi: 10.1111/j.1365-2559.1992.tb00340.x.

DOI:10.1111/j.1365-2559.1992.tb00340.x

PMID:1634200

Abstract

Eleven colloid cysts of the third ventricle were investigated by immunohistochemistry using 16 mono- and polyclonal antibodies. Colloid cyst epithelium, choroid plexus epithelium and ependyma showed different immunohistochemical profiles. In particular, antibodies to different cytokeratins and to transthyretin revealed considerable and constant differences of immunoreactivity. Therefore, common derivation of the three tissues seems unlikely. Our findings are interpreted in favour of the non-neuroepithelial origin of third ventricular colloid cysts.

摘要

使用16种单克隆和多克隆抗体，通过免疫组织化学方法对11个第三脑室的胶样囊肿进行了研究。胶样囊肿上皮、脉络丛上皮和室管膜显示出不同的免疫组织化学特征。特别是，针对不同细胞角蛋白和转甲状腺素蛋白的抗体显示出免疫反应性的显著且恒定的差异。因此，这三种组织似乎不太可能有共同的起源。我们的研究结果支持第三脑室胶样囊肿的非神经上皮起源。