Kessler H, Haase B
Technical University of Munich, Institute of Organic Chemistry, Garching, Federal Republic of Germany.
Int J Pept Protein Res. 1992 Jan;39(1):36-40. doi: 10.1111/j.1399-3011.1992.tb01553.x.
Six diastereoisomeric cyclic hexapeptides of the partial sequence 39-44 of human thymopoietin III in which each residue was replaced with the D-amino acid were synthesized. In contrast to expectations, the yields from cyclization were not influenced by the location of the D-residue.
合成了六种非对映异构的环状六肽,其为人胸腺生成素III 39-44部分序列,其中每个残基都被D-氨基酸取代。与预期相反,环化产率不受D-残基位置的影响。