Kansu Tulay, Kadayifcilar Sibel
Department of Neurology-Neuro-Ophthalmology Unit, Hacettepe University, School of Medicine, Ankara 06100, Turkey.
Curr Treat Options Neurol. 2006 Jan;8(1):81-8. doi: 10.1007/s11940-996-0026-6.
Behçet's disease is a systemic vasculitis characterized by recurrent oral and genital ulcers and ocular inflammation. The disease may also involve the joints, skin, central nervous system, the lungs, and gastrointestinal tract. Ocular manifestations include anterior uveitis, posterior uveitis, macular edema, retinal vasculitis, conjunctival ulcers, optic neuropathy, papilledema, secondary glaucoma, cataract, and neovascularization of iris or retina. The cause of Behçet's disease is unknown, but autoimmune and genetic factors are considered important in its pathogenesis. Promising new imaging techniques and treatments are available to provide better management for patients. This review focuses on recent data on visual aspects, pathogenesis, and the treatment of Behçet's disease.
白塞病是一种全身性血管炎,其特征为复发性口腔和生殖器溃疡以及眼部炎症。该疾病还可能累及关节、皮肤、中枢神经系统、肺部和胃肠道。眼部表现包括前葡萄膜炎、后葡萄膜炎、黄斑水肿、视网膜血管炎、结膜溃疡、视神经病变、视乳头水肿、继发性青光眼、白内障以及虹膜或视网膜新生血管形成。白塞病的病因尚不清楚,但自身免疫和遗传因素在其发病机制中被认为很重要。有前景的新成像技术和治疗方法可用于为患者提供更好的管理。本综述重点关注白塞病视觉方面、发病机制和治疗的最新数据。