一例以中枢性神经源性过度通气为表现的神经白塞病
A Case of Neuro-Behcet's Disease Presenting with Central Neurogenic Hyperventilation.
作者信息
Alkhachroum Ayham M, Saeed Saba, Kaur Jaspreet, Shams Tanzila, DeGeorgia Michael A
机构信息
Department of Neurology, University Hospitals Case Medical Center, Cleveland, OH, USA.
出版信息
Am J Case Rep. 2016 Mar 11;17:154-9. doi: 10.12659/ajcr.895382.
BACKGROUND
Behcet's disease is a chronic inflammatory disorder usually characterized by the triad of oral ulcers, genital ulcers, and uveitis. Central to the pathogenesis of Behcet's disease is an autoimmune vasculitis. Neurological involvement, so called "Neuro-Behcet's disease", occurs in 10-20% of patients, usually from a meningoencephalitis or venous thrombosis.
CASE REPORT
We report the case of a 46-year-old patient with Neuro-Behcet's disease who presented with central neurogenic hyperventilation as a result of brainstem involvement from venulitis.
CONCLUSIONS
To the best of our knowledge, central neurogenic hyperventilation has not previously been described in a patient with Neuro-Behcet's disease.
背景
白塞病是一种慢性炎症性疾病，通常以口腔溃疡、生殖器溃疡和葡萄膜炎三联征为特征。白塞病发病机制的核心是自身免疫性血管炎。神经系统受累，即所谓的“神经白塞病”，发生在10% - 20%的患者中，通常源于脑膜脑炎或静脉血栓形成。
病例报告
我们报告一例46岁神经白塞病患者的病例，该患者因小静脉炎累及脑干而出现中枢性神经源性通气过度。
结论
据我们所知，此前尚未在神经白塞病患者中描述过中枢性神经源性通气过度。
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