Pfeifer Heidi H, Thiele Elizabeth A
Pediatric Epilepsy Program, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Neurology. 2005 Dec 13;65(11):1810-2. doi: 10.1212/01.wnl.0000187071.24292.9e.
The ketogenic diet is often effective for intractable epilepsy, but many patients have trouble complying with the strict regimen. The authors tested an alternative diet regimen, a low-glycemic-index treatment, with more liberal total carbohydrate intake but restricted to foods that produce relatively little increase in blood glucose (glycemic index < 50). Ten of 20 patients treated with this regimen experienced a greater than 90% reduction in seizure frequency.
生酮饮食通常对难治性癫痫有效，但许多患者难以遵守严格的饮食方案。作者测试了一种替代饮食方案，即低血糖指数治疗，总碳水化合物摄入量更为宽松，但仅限于食用那些使血糖升高相对较少的食物（血糖指数<50）。接受该方案治疗的20名患者中有10名癫痫发作频率降低了90%以上。
