Murphy Patricia
University of Toronto, Department of Pharmacology, Medical Sciences Building, 1 King's College Circle, Toronto, Ontario, M5S 1A8, Canada.
Expert Rev Neurother. 2005 Nov;5(6):769-75. doi: 10.1586/14737175.5.6.769.
The ketogenic diet is a high-fat, low-carbohydrate and low-protein diet used in the treatment of epilepsy that does not respond to antiepileptic drugs. The diet has been found to be very effective in treating intractable epilepsy in children. There is also some evidence that the diet is useful in treating drug-resistant epilepsy in infants, adolescents and adults. This paper traces the history and development of the ketogenic diet and reviews the clinical and animal research investigating its effects.
生酮饮食是一种高脂肪、低碳水化合物和低蛋白质的饮食,用于治疗对抗癫痫药物无反应的癫痫。已发现该饮食在治疗儿童难治性癫痫方面非常有效。也有一些证据表明,该饮食在治疗婴儿、青少年和成人的耐药性癫痫方面有用。本文追溯了生酮饮食的历史和发展,并综述了研究其效果的临床和动物研究。