Dokianakis Spiros N, Kornaros Michael, Lyberatos Gerasimos
Department of Chemical Engineering, University of Patras, Karatheodori st. 1, 26500 Patras, Greece.
Biotechnol Bioeng. 2006 Mar 5;93(4):718-26. doi: 10.1002/bit.20758.
A simple kinetic model was developed for describing nitrite oxidation by autotrophic aerobic nitrifiers in a continuous stirred tank reactor (CSTR), in which mixed (suspended and attached) growth conditions prevail. The CSTR system was operated under conditions of constant nitrite feed concentration and varying volumetric flow rates. Experimental data from steady-state conditions in the CSTR system and from batch experiments were used for the determination of the model's kinetic parameters. Model predictions were verified against experimental data obtained under transient operating conditions, when volumetric flow rate and nitrite feed concentration disturbances were imposed on the CSTR. The presented kinetic modeling procedure is quite simple and general and therefore can also be applied to other mixed growth biological systems.
开发了一个简单的动力学模型，用于描述连续搅拌釜式反应器（CSTR）中自养好氧硝化菌对亚硝酸盐的氧化过程，该反应器中存在混合（悬浮和附着）生长条件。CSTR系统在亚硝酸盐进料浓度恒定和体积流量变化的条件下运行。来自CSTR系统稳态条件和间歇实验的实验数据用于确定模型的动力学参数。当对CSTR施加体积流量和亚硝酸盐进料浓度干扰时，根据瞬态运行条件下获得的实验数据对模型预测进行了验证。所提出的动力学建模程序相当简单且通用，因此也可应用于其他混合生长生物系统。
