Microbiology Program, The Pennsylvania State University, University Park, Pennsylvania 16802.
Appl Environ Microbiol. 1987 Jul;53(7):1515-8. doi: 10.1128/aem.53.7.1515-1518.1987.
Nonobligate bacterial predator strain N-1 was highly resistant to copper. In fact, it required more than minimal amounts of copper to initiate growth, but not for growth that followed growth initiation. Strain N-1 made a peptide growth initiation factor (GIF) to marshal copper from its environment for growth initiation. Production of this GIF occurred before the onset of growth initiation, but production was shut down if excess copper was present. At high copper levels, the time required for onset of growth initiation was directly related to the amount of copper that was present. At low copper levels, a similar graded response occurred for increments of added GIF. Agromyces ramosus is a predator in its own right, but it also is a prey species for strain N-1. A. ramosus was found to be very sensitive to copper and to the copper GIF produced by N-1. It is possible that the copper GIF is the means used by N-1 to kill A. ramosus.
非专性细菌捕食菌株 N-1 对铜具有很强的抗性。事实上，它需要超过最小量的铜来启动生长，但不需要用于生长启动后的生长。菌株 N-1 产生一种肽生长起始因子（GIF），将铜从其环境中召集起来用于生长启动。这种 GIF 的产生发生在生长起始之前，但如果存在过量的铜，生产就会关闭。在高铜水平下，生长起始所需的时间与存在的铜量直接相关。在低铜水平下，对于添加的 GIF 的增量也会出现类似的分级响应。节旋藻是一种自身的捕食者，但它也是 N-1 菌株的猎物。发现节旋藻对铜和 N-1 产生的铜 GIF 非常敏感。N-1 可能使用铜 GIF 来杀死节旋藻。
