黄曲霉毒素的微生物解毒作用。
Microbial detoxification of aflatoxin.
作者信息
Ciegler A, Lillehoj E B, Peterson R E, Hall H H
机构信息
Northern Regional Research Laboratory, Northern Utilization Research and Development Division, U.S. Department of Agriculture, Peoria, Illinois.
出版信息
Appl Microbiol. 1966 Nov;14(6):934-9. doi: 10.1128/am.14.6.934-939.1966.
Abstract
Yeasts, molds, bacteria, actinomycetes, algae, and fungal spores were screened for their ability to degrade aflatoxin. Some molds and mold spores partially transformed aflatoxin B(1) to new fluorescing compounds. Only one of the bacteria, Flavobacterium (aurantiacum?) NRRL B-184, removed aflatoxin from solution. Both growing and resting cells of B-184 took up toxin irreversibly. Toxin-contaminated milk, oil, peanut butter, peanuts, and corn were completely detoxified, and contaminated soybean was partially detoxified by addition of B-184. Duckling assays showed that detoxification of aflatoxin solutions by B-184 was complete, with no new toxic products being formed.
摘要
对酵母、霉菌、细菌、放线菌、藻类和真菌孢子降解黄曲霉毒素的能力进行了筛选。一些霉菌和霉菌孢子将黄曲霉毒素B(1)部分转化为新的荧光化合物。只有一种细菌，即黄杆菌（橙色黄杆菌？）NRRL B - 184，能从溶液中去除黄曲霉毒素。B - 184的生长细胞和静止细胞都不可逆地摄取毒素。通过添加B - 184，受毒素污染的牛奶、油、花生酱、花生和玉米被完全解毒，受污染的大豆被部分解毒。雏鸭试验表明，B - 184对黄曲霉毒素溶液的解毒是完全的，没有形成新的有毒产物。
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