Chernousov A F, Khorobrykh T V, Antonov O N
Khirurgiia (Mosk). 2005(12):25-9.
Experimental and clinical results of use of fibrin glue for strengthening "high risk" sutures of anastomoses in elective surgery of the esophagus, stomach and urgent abdominal surgery are presented. In experimental studies this glue permitted to increase mechanical strength and containment of anastomosis, to accelerate microbial elimination, activated reparative processes. In clinical practice fibrin glue permitted to avoid suture insufficiency of gastrointestinal anastomoses in the most unfavorable conditions (peritonitis, acute intestinal obstruction, oncological process, etc). It is concluded that fibrin glue is the high effective protective agent for gastrointestinal anastomoses.
本文介绍了在食管、胃择期手术以及腹部急症手术中，使用纤维蛋白胶强化“高危”吻合口缝线的实验和临床结果。在实验研究中，这种胶水能够增强吻合口的机械强度和密封性，加速微生物清除，激活修复过程。在临床实践中，纤维蛋白胶能够在最不利的情况下（如腹膜炎、急性肠梗阻、肿瘤病变等）避免胃肠吻合口缝线不足。结论是，纤维蛋白胶是胃肠吻合口的高效保护剂。
