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腹腔镜胃旁路术后横纹肌溶解症

Rhabdomyolysis following laparoscopic gastric bypass.

作者信息

Filis D, Daskalakis M, Askoxylakis I, Metaxari M, Melissas J

机构信息

Bariatric Unit, Department of Surgical Oncology, Medical School, University of Crete, Heraklion, Crete, Greece.

出版信息

Obes Surg. 2005 Nov-Dec;15(10):1496-500. doi: 10.1381/096089205774859317.

Abstract

Rhabdomyolysis is a rare complication of serious surgical procedures, and constitutes a clinical and biochemical syndrome, caused by injury and destruction of skeletal muscles. It is accompanied by pain in the region of the referred muscle group, increase in creatine phosphokinase levels, myoglobinuria, often with severe renal failure, and finally multi-organ system failure and death, if not treated in time. The main risk factor in the development of postoperative rhabdomyolysis is prolonged intraoperative immobilization of the patient. Morbidly obese patients who undergo laparoscopic bariatric operations should be considered high-risk for rhabdomyolysis, from extended immobilization and pressure phenomena in the lumbar region and gluteal muscles. We report a 20-year-old woman with BMI 51, who underwent a prolonged laparoscopic Roux-en-Y gastric bypass. Postoperatively, she presented severe myalgia in the gluteal muscles and lumbar region, oliguria and creatine phosphokinase levels that reached 38,700 U/L. She was treated with intensive hydration and analgesics, and did not develop acute renal failure because diagnosis and treatment were attained immediately.

摘要

横纹肌溶解症是严重外科手术中一种罕见的并发症,是由骨骼肌损伤和破坏引起的临床及生化综合征。其伴随症状包括受累肌群区域疼痛、肌酸磷酸激酶水平升高、肌红蛋白尿,常伴有严重肾衰竭,若不及时治疗最终会导致多器官系统衰竭和死亡。术后横纹肌溶解症发生的主要危险因素是患者术中长时间固定不动。接受腹腔镜减肥手术的病态肥胖患者,由于腰部和臀肌长时间固定及受压现象,应被视为横纹肌溶解症的高危人群。我们报告一例20岁、体重指数为51的女性患者,她接受了长时间的腹腔镜Roux-en-Y胃旁路手术。术后,她出现了臀肌和腰部严重肌痛、少尿,肌酸磷酸激酶水平达到38,700 U/L。她接受了强化补液和镇痛治疗,由于诊断和治疗及时,未发生急性肾衰竭。

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