Suppr超能文献

病态肥胖患者腹腔镜胃旁路术后横纹肌溶解症

Postoperative rhabdomyolysis following laparoscopic gastric bypass in the morbidly obese.

作者信息

Khurana Rahul N, Baudendistel Thomas E, Morgan Elise F, Rabkin Robert A, Elkin Ronald B, Aalami Oliver O

机构信息

Departments of Medicine, California Pacific Medical Center, San Francisco, USA.

出版信息

Arch Surg. 2004 Jan;139(1):73-6. doi: 10.1001/archsurg.139.1.73.

Abstract

HYPOTHESIS

Laparoscopic approaches for weight reduction in the morbidly obese have become common with more than 50,000 bariatric surgical procedures being performed in 2001. The objective of this article is to raise awareness among surgeons of a new complication of rhabdomyolysis from this frequent procedure.

DESIGN

Case series extracted from surgical database from January 2, 2001, through December 31, 2002.

PATIENTS AND METHODS

We identified 5 cases of postoperative rhabdomyolysis in morbidly obese patients who underwent laparoscopic duodenal switch procedures with parietal gastrectomy. The cause, pathogenesis, and clinical features are reviewed and discussed.

RESULTS

Postoperative rhabdomyolysis developed in 5 of 353 morbidly obese patients who underwent consecutive laparoscopic duodenal switch procedures, an incidence of 1.4%. All 5 patients were male, had a mean peak serum creatine kinase level of 19 680 U/L, and reported muscle pain in either the buttock, hip, or shoulder regions during the early postoperative period.

CONCLUSIONS

We hypothesized that morbidly obese patients develop critical surface and deep tissue pressures during bariatric surgery, increasing their risk for tissue injury and rhabdomyolysis. Unexplained elevations in the serum creatinine level or reports of buttock, hip, or shoulder pain in the postoperative period should raise the possibility of rhabdomyolysis and prompt clinical investigation. We recommend routine preoperative and postoperative measurements of the serum creatine kinase and serum creatinine levels to aid detection. Surgeons need to keep a low index of suspicion because early diagnosis and treatment are the cornerstones of successful management of rhabdomyolysis.

摘要

假说

腹腔镜手术用于病态肥胖患者减重已很常见,2001年有超过50000例减肥手术实施。本文的目的是提高外科医生对这种常见手术引发的一种新的横纹肌溶解并发症的认识。

设计

从2001年1月2日至2002年12月31日的手术数据库中提取的病例系列。

患者与方法

我们确定了5例病态肥胖患者术后发生横纹肌溶解,这些患者接受了腹腔镜十二指肠转位术加胃壁切除术。对病因、发病机制和临床特征进行了回顾和讨论。

结果

在连续接受腹腔镜十二指肠转位术的353例病态肥胖患者中,有5例发生了术后横纹肌溶解,发生率为1.4%。所有5例患者均为男性,血清肌酸激酶平均峰值水平为19680 U/L,且均报告在术后早期臀部、髋部或肩部区域有肌肉疼痛。

结论

我们推测病态肥胖患者在减肥手术期间会出现临界的体表和深部组织压力,增加了组织损伤和横纹肌溶解的风险。术后血清肌酐水平不明原因升高或报告臀部、髋部或肩部疼痛应提高横纹肌溶解的可能性并促使进行临床调查。我们建议术前和术后常规测量血清肌酸激酶和血清肌酐水平以协助检测。外科医生需要保持较低的怀疑指数,因为早期诊断和治疗是成功处理横纹肌溶解的基石。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验