Sja'bani Mohammad, Asdie Ahmad H, Widayati Kartika, Subroto Yanri, Kariadi Sri Hks, Arifin Agusta Y L, Adhiarta I G N, Permana Hikmat, T Askandar, Adi Soebagijo, Wibisono Sony, Murtiwi Sri
Department of Internal Medicine, Sardjito Hospital, Faculty of Medicine, University of Gadjah Mada,Yogyakarta, Indonesia.
Acta Med Indones. 2005 Oct-Dec;37(4):199-204.
To assess the prevalence of macroalbuminuria and microalbuminuria in hypertensive patients with type 2 diabetes in 10 Asian countries.
This cross-sectional clinic-based epidemiological study is a subanalysis of data collected from patients attending three medical centres in Indonesia from May 2002 to October 2002. A total of 207 patients were enrolled, of which 177 patients constituted the per protocol population (patients with bacteriuria and haematuria were excluded).
Overall, the prevalence of diabetic kidney disease was high, with macroalbuminuria comprising 44.7% (41.2-48.1;95% confidence interval) and microalbuminuria comprising 33.0% (29.7-36.3; 95% confidence interval). While the majority (91.53%) of patients were receiving treatment for hypertension, only 6.21% of the patients had systolic/diastolic blood pressures below the 130/85 mmHg target.
The prevalence of microalbuminuria and macroalbuminuria was high in hypertensive patients with type 2 diabetes in Indonesia, which is indicative of an impending pandemic of diabetic cardiovascular and renal diseases in the region.
评估10个亚洲国家2型糖尿病高血压患者中大量白蛋白尿和微量白蛋白尿的患病率。
这项基于门诊的横断面流行病学研究是对2002年5月至2002年10月期间在印度尼西亚三个医疗中心就诊的患者收集的数据进行的亚分析。共纳入207例患者,其中177例患者构成符合方案人群(排除了有菌尿和血尿的患者)。
总体而言,糖尿病肾病的患病率很高,大量白蛋白尿占44.7%(41.2 - 48.1;95%置信区间),微量白蛋白尿占33.0%(29.7 - 36.3;95%置信区间)。虽然大多数患者(91.53%)正在接受高血压治疗,但只有6.21%的患者收缩压/舒张压低于130/85 mmHg的目标值。
印度尼西亚2型糖尿病高血压患者中微量白蛋白尿和大量白蛋白尿的患病率很高,这表明该地区即将爆发糖尿病心血管和肾脏疾病大流行。