Schultze-Werninghaus Gerhard
Berufsgenossenschaftliche Kliniken Bergmannsheil, Medizinische Klinik III Pneumologie, Allergologie, Schlaf- und Beatmungsmedizin, Klinikum der Ruhr-Universität Bochum, Bochum, Germany.
Chem Immunol Allergy. 2006;91:16-29. doi: 10.1159/000090227.
Sojourns in the high mountains have been recommended by specialists for patients with asthma since many decades. An inquiry among physicians of the 'Davoser Arzteverein' revealed as early as 1906 that 133/143 patients with bronchial asthma had no or only few asthma attacks during their stay in Davos, and that 81% had a persistent improvement of their disease. These early observations about effects of the alpine climate were, of course, reported at a time, when the spectrum of pharmacotherapy was very limited. However, these observations were consistent and were therefore regarded as proof for the therapeutic value of sojourns under alpine conditions in bronchial asthma. In recent years, however, the indication for asthma treatment in high mountains is increasingly questioned, in particular by health insurance systems. Therefore it is the aim of this contribution to summarize the available data about the effects of a stay of asthmatic patients at 1,500-1,800 m above sea level. It is concluded that the available evidence suggests a significant beneficial effect of high altitude in bronchial asthma, in particular in steroid-dependent patients.
几十年来,专家们一直建议哮喘患者前往高山地区疗养。早在1906年,对“达沃斯医生协会”的医生进行的一项调查显示,143名支气管哮喘患者中有133名在达沃斯逗留期间没有或仅有很少的哮喘发作,81%的患者病情持续改善。当然,这些关于高山气候影响的早期观察报告是在药物治疗范围非常有限的时期。然而,这些观察结果是一致的,因此被视为高山环境下疗养对支气管哮喘具有治疗价值的证据。然而,近年来,在高山地区进行哮喘治疗的适应症越来越受到质疑,尤其是受到医疗保险系统的质疑。因此,本论文的目的是总结关于哮喘患者在海拔1500 - 1800米处逗留的影响的现有数据。得出的结论是,现有证据表明高海拔对支气管哮喘有显著的有益影响,尤其是对依赖类固醇的患者。