Obara Tercio, Munin Egberto, Libert Edson A, Pompeu Eduardo, Pacheco Marcos Tadeu T
Instituto de Pesquisa & Desenvolvimento (IPD), Universidade do Vale do Paraíba, UNIVAP, São José dos Campos, SP, Brazil.
Photomed Laser Surg. 2005 Dec;23(6):561-6. doi: 10.1089/pho.2005.23.561.
The purpose of this work is to investigate the morphological changes of the rabbit tibia bone submitted to osteotomy with XeCl excimer laser.
Laser ablation of tissue is a relevant clinical application of high-power lasers. Due to the variety of laser wavelengths and properties of biological targets, the subject has not yet been completely explored.
In this study, four tibias were irradiated with six different durations. The applied energy density was 6.7 J/cm(2) per pulse at a 4-Hz repetition rate.
The 24 samples had similar and well-defined craters that were free of carbonization. The ablation rates per pulse, at 60-120 seconds, were 3.8 and 1.9 microm at the compact bone and the marrow tissue, respectively. The ablation process ceased after 120 sec, with a 1.6-mm crater depth.
In the present study, the laser used showed a self-limiting characteristic, which is a phenomenon that can be of great value in preserving important structures close to the working area, giving a margin of safety to the surgeon, in case of over-irradiation. This self-limiting effect is attributed to liquid filling the cavity by the bleeding and irrigation process.
本研究旨在探讨用氙氯准分子激光进行截骨术后兔胫骨的形态学变化。
组织激光消融是高功率激光的一项重要临床应用。由于激光波长的多样性和生物靶点的特性，该领域尚未得到充分探索。
本研究中，对四根胫骨进行了六种不同时长的照射。以4赫兹的重复频率施加的能量密度为每脉冲6.7焦耳/平方厘米。
24个样本有相似且边界清晰的凹坑，无碳化现象。在60 - 120秒时，致密骨和骨髓组织的每脉冲消融率分别为3.8微米和1.9微米。120秒后消融过程停止，凹坑深度为1.6毫米。
在本研究中，所使用的激光显示出自我限制特性，这种现象在保护靠近工作区域的重要结构方面具有重要价值，在过度照射的情况下为外科医生提供了安全边际。这种自我限制效应归因于出血和冲洗过程使液体填充了腔隙。
