King Daniel A, Almog Yaniv
Division of Pulmonary and Critical Care Medicine, University of Maryland Medical Center, Baltimore, MD, USA.
Crit Care. 2005;9(6):634-5. doi: 10.1186/cc3893. Epub 2005 Nov 2.
Cardiac troponins are highly sensitive and specific indicators of myocardial injury. Although the mechanism of this injury is not entirely clear, it carries important prognostic information. Elevated serum levels of cardiac troponins have been described in a wide variety of conditions other than myocardial infarction (MI). The current study is an important first step in trying to determine the exact frequency of MI among critically ill patients with elevated troponin. At present, the rate of MI in these patients is unknown and its implications on outcome and management will have to await future prospective clinical trials.
心肌肌钙蛋白是心肌损伤高度敏感且特异的指标。尽管这种损伤的机制尚不完全清楚,但它携带重要的预后信息。除心肌梗死(MI)外,多种情况下血清心肌肌钙蛋白水平都会升高。当前研究是试图确定肌钙蛋白升高的重症患者中MI确切发生率的重要第一步。目前,这些患者中MI的发生率尚不清楚,其对预后和治疗的影响有待未来的前瞻性临床试验。