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解读月经初潮平均年龄的持续下降:来自两项间隔10年对美国女孩进行的全国代表性调查的结果。

Interpreting the continued decline in the average age at menarche: results from two nationally representative surveys of U.S. girls studied 10 years apart.

作者信息

Anderson Sarah E, Must Aviva

机构信息

Gerald J. and Dorothy R. Friedman School of Nutrition Science and Technology and the Department of Public Health and Family Medicine, Tufts University, Boston, Massachusetts 02111, USA.

出版信息

J Pediatr. 2005 Dec;147(6):753-60. doi: 10.1016/j.jpeds.2005.07.016.

Abstract

OBJECTIVES

To determine whether average age at menarche declined in the United States during the past decade, and whether associations between menarcheal timing, weight status, and race/ethnicity changed.

STUDY DESIGN

Relative weight, race/ethnicity, and menarcheal status of girls (n = 1577) in the National Health and Nutrition Examination Survey (NHANES) III (1988-1994) were compared with those of girls (n = 1720) in NHANES 1999-2002. Probit analysis estimated average age at menarche overall and also by race/ethnicity. Logistic regression assessed associations of relative weight and race/ethnicity with menarcheal status.

RESULTS

In the United States, average age at menarche declined from 12.53 years (95% confidence interval [CI] = 12.43 to 12.63 years) in 1988-1994 to 12.34 years (95% CI = 12.24 to 12.45 years) in 1999-2002. By race/ethnicity, average age at menarche estimates were as follows: non-Hispanic whites, 12.57 years (95% CI = 12.45 to 12.69 years) and 12.52 years (95% CI = 12.38 to 12.67 years); non-Hispanic blacks, 12.09 years (95% CI = 11.82 to 12.36 years) and 12.06 years (95% CI = 11.81 to 12.32 years); and Mexican Americans, 12.24 years (95% CI = 11.88 to 12.59 years) and 12.09 years (95% CI = 11.81 to 12.37 years). Higher relative weight was consistently associated with increased likelihood of having reached menarche.

CONCLUSIONS

Average age at menarche in the United States declined by 2.3 months between 1988-1994 and 1999-2002; by race/ethnicity, declines were considerably smaller. Changes in the population distribution of race/ethnicity and relative weight should be considered when interpreting trends in age at menarche.

摘要

目的

确定在过去十年间美国女孩的初潮平均年龄是否下降,以及初潮时间、体重状况和种族/族裔之间的关联是否发生变化。

研究设计

将国家健康与营养检查调查(NHANES)III(1988 - 1994年)中1577名女孩的相对体重、种族/族裔和初潮状况,与1999 - 2002年NHANES中1720名女孩的这些指标进行比较。概率分析估计总体以及按种族/族裔划分的初潮平均年龄。逻辑回归评估相对体重和种族/族裔与初潮状况之间的关联。

结果

在美国,初潮平均年龄从1988 - 1994年的12.53岁(95%置信区间[CI]=12.43至12.63岁)降至1999 - 2002年的12.34岁(95%CI = 12.24至12.45岁)。按种族/族裔划分,初潮平均年龄估计如下:非西班牙裔白人,12.57岁(95%CI = 12.45至12.69岁)和12.52岁(95%CI = 12.38至12.67岁);非西班牙裔黑人,12.09岁(95%CI = 11.82至12.36岁)和12.06岁(95%CI = 11.81至12.32岁);墨西哥裔美国人,12.24岁(95%CI = 11.88至12.59岁)和12.09岁(95%CI = 11.81至12.37岁)。相对体重较高始终与初潮发生的可能性增加相关。

结论

1988 - 1994年至1999 - 2002年间,美国女孩的初潮平均年龄下降了2.3个月;按种族/族裔划分,下降幅度要小得多。在解释初潮年龄趋势时,应考虑种族/族裔和相对体重的人口分布变化。

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