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1927 年至 2004 年出生的韩国女性初潮年龄的时间趋势:一项基于人群的研究。

Temporal trend of age at menarche in Korean females born between 1927 and 2004: a population-based study.

机构信息

Department of Pediatrics, Chung-Ang University Hospital, Seoul, Republic of Korea.

Department of Pediatrics, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.

出版信息

Front Endocrinol (Lausanne). 2024 Jun 4;15:1399984. doi: 10.3389/fendo.2024.1399984. eCollection 2024.

Abstract

BACKGROUNDS

The age at menarche has decreased worldwide. Previous studies on Korean adolescents have reported a downward trend in age at menarche. This study aimed to investigate the current trends in age at menarche among Korean adolescents using nationally representative data.

MATERIALS AND METHODS

The study used data from the Korea National Health and Nutrition Examination Survey 2007-2021. A total of 50,730 females born between 1927 and 2004 with information on age at menarche were included. The trend in age at menarche was analyzed according to 15 birth-year groups (with 5-year intervals) using quantile regression analysis.

RESULTS

The mean age at menarche decreased from 16.92 ± 0.06 years for females born before 1935 to 12.45 ± 0.04 years for females born between 2000 and 2004 ( <.001). According to the percentile group of age at menarche, mean menarche age decreased by -0.071 years per year (95% confidence interval [CI], -0.072 to -0.070) in total, -0.050 years per year (95% CI, -0.052 to -0.048) in the 3rd percentile group, -0.088 years per year (95% CI, -0.091 to -0.085) in the 97th percentile group ( <.001 for all). A decreasing trend of age at menarche was more prominent in the obesity group (-0.080 years per year, 95% CI, -0.082 to -0.078) compared to the non-obesity group (-0.069 years per year, 95% CI, -0.071 to -0.068) ( <.001 for both).

CONCLUSION

Ongoing downward trend in age at menarche was observed in Korean females born until 2004, decreasing by 0.71 years per decade. The downward trend was faster in individuals with a higher percentile of age at menarche and in those with obesity.

摘要

背景

全球范围内,女性初潮年龄有所提前。此前针对韩国青少年的研究报告称,初潮年龄呈下降趋势。本研究旨在利用全国代表性数据,调查韩国青少年初潮年龄的最新趋势。

材料与方法

本研究使用了 2007-2021 年韩国国家健康与营养检查调查的数据。共纳入了 50730 名出生于 1927 年至 2004 年、且有初潮年龄信息的女性。使用定量回归分析,按 15 个出生年份组(每 5 年一组)分析初潮年龄的变化趋势。

结果

1935 年前出生的女性初潮年龄为 16.92±0.06 岁,而 2000-2004 年出生的女性初潮年龄为 12.45±0.04 岁(<0.001)。按照初潮年龄的百分位分组,总的来说,初潮年龄每年减少-0.071 岁(95%置信区间[CI]:-0.072 至-0.070),第 3 百分位组每年减少-0.050 岁(95%CI:-0.052 至-0.048),第 97 百分位组每年减少-0.088 岁(95%CI:-0.091 至-0.085)(均<0.001)。与非肥胖组(每年减少-0.069 岁,95%CI:-0.071 至-0.068)相比,肥胖组(每年减少-0.080 岁,95%CI:-0.082 至-0.078)的初潮年龄下降趋势更为明显(均<0.001)。

结论

直到 2004 年出生的韩国女性初潮年龄呈持续下降趋势,每十年减少 0.71 岁。在初潮年龄百分位较高的个体和肥胖个体中,下降趋势更快。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f24c/11182987/cb7158484824/fendo-15-1399984-g001.jpg

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