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大鼠内侧前额叶皮质GABA中间神经元中GAD mRNA的表达。

Expression of GAD mRNA in GABA interneurons of the rat medial frontal cortex.

作者信息

Rétaux S, Julien J F, Besson M J, Penit-Soria J

机构信息

Laboratoire de Neurochimie-Anatomie, Université Paris 6-Pierre et Marie Curie, France.

出版信息

Neurosci Lett. 1992 Feb 17;136(1):67-71. doi: 10.1016/0304-3940(92)90649-r.

DOI:10.1016/0304-3940(92)90649-r
PMID:1635668
Abstract

The distribution of glutamic acid decarboxylase (GAD) mRNA containing cells was studied in the rat medial frontal cortex (MFC). The neurons labelled by the 35S-labelled cDNA probe were distributed uniformly throughout all the layers and represented 16% of the total neuronal population. It was possible to distinguish two cell populations expressing high and low levels of GAD mRNA corresponding to 63% and 27% of labelled cells, respectively. Concerning the laminar distribution of these two populations of GAD mRNA containing neurons, no marked difference was observed between the various areas of the MFC.

摘要

对大鼠内侧额叶皮质(MFC)中含谷氨酸脱羧酶(GAD)mRNA的细胞分布进行了研究。用35S标记的cDNA探针标记的神经元均匀分布于所有层,占神经元总数的16%。可以区分出表达高水平和低水平GAD mRNA的两类细胞群,分别占标记细胞的63%和27%。关于这两类含GAD mRNA神经元的层状分布,在MFC的不同区域未观察到明显差异。

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