Bell W E
Department of Pediatrics and Neurology, University of Iowa College of Medicine, Iowa City.
Pediatr Clin North Am. 1992 Aug;39(4):651-68. doi: 10.1016/s0031-3955(16)38369-9.
Accumulating clinical experience has gradually outlined the epidemiology of acute bacterial meningitis, including the epidemic and the sporadic forms, the customary clinical signs related to different age groups and causative organisms, and methods of rapid diagnosis by laboratory examinations. Effective treatment, which continues to evolve, emerged in the 1940s with the development of antibacterial antimicrobials, first with the sulfonamides and then with the penicillins. The literature relative to these aspects of the disease has been abundant in the past few years. This article is directed to a variety of topics that have direct bearing on the disorder but are less often addressed to those who deal with infants and children.
不断积累的临床经验逐渐勾勒出急性细菌性脑膜炎的流行病学特征,包括流行型和散发型、与不同年龄组及致病病原体相关的常见临床体征,以及通过实验室检查进行快速诊断的方法。随着抗菌药物的发展,有效的治疗方法在20世纪40年代开始出现,先是磺胺类药物,然后是青霉素。在过去几年里,关于该疾病这些方面的文献大量涌现。本文针对与该疾病直接相关但较少为处理婴幼儿问题的人员所涉及的各种主题。