Gama Mirnaluci P Ribeiro, Pellegrinello Silviane, Alonso Sheyla Santos Quelle, Coelho Juliana Filus, Martins Caroline F Luz, Biagini Gleyne Lopes Kujew
Departamento de Medicina Interna, Faculdade Evangélica do Paraná, Hospital Universitário Evangélico de Curitiba, Curitiba, RS.
Arq Bras Endocrinol Metabol. 2005 Aug;49(4):604-9. doi: 10.1590/s0004-27302005000400021. Epub 2005 Oct 19.
Rhabdomyolysis has been the theme in medical literature for the last fifty years. In these last decades, with statins being used in primary and secondary cardiovascular prevention events, this theme returns and statins are now pointed as the trigger to this almost always fatal complication. Rhabdomyolysis due to statins administration occurs mainly in association with other drugs. Our case reports on a patient with fatal statin-induced rhabdomyolysis whose medical history included diffuse atherosclerotic disease.
在过去五十年里,横纹肌溶解症一直是医学文献中的主题。在过去几十年中,随着他汀类药物用于一级和二级心血管预防事件,这个主题再次出现,现在他汀类药物被指认为这种几乎总是致命并发症的诱因。因服用他汀类药物导致的横纹肌溶解症主要与其他药物联合发生。我们报告了一例因他汀类药物诱发致命横纹肌溶解症的患者,其病史包括弥漫性动脉粥样硬化疾病。