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健康成年人因肠道同工酶导致碱性磷酸酶异常升高。

Unusually high alkaline phosphatase due to intestinal isoenzyme in a healthy adult.

作者信息

Cho Sung R, Lim Young A, Lee Wee G

机构信息

Department of Laboratory Medicine, Ajou University School of Medicine, Suwon, Republic of Korea.

出版信息

Clin Chem Lab Med. 2005;43(11):1274-5. doi: 10.1515/CCLM.2005.218.

DOI:10.1515/CCLM.2005.218
PMID:16358445
Abstract

Intestinal alkaline phosphatase (ALP) is more prevalent in individuals of blood group O or B, and increases after a meal, especially on a high-fat diet. We did not realize that clinicians could underestimate the importance of fasting for ALP measurement until one healthy adult showed a huge difference in ALP levels before and after a meal. We report a case of transient hyperphosphatasemia resulting in unnecessary workup due to intestinal ALP in a healthy adult of blood group O.

摘要

肠道碱性磷酸酶(ALP)在O型或B型血的个体中更为普遍,并且在进食后会升高,尤其是在高脂饮食后。直到一名健康成年人在进食前后的ALP水平出现巨大差异,我们才意识到临床医生可能低估了空腹对ALP测量的重要性。我们报告了一例因肠道ALP导致的短暂性高磷酸酶血症病例,该病例发生在一名健康的O型血成年人身上,导致了不必要的检查。

相似文献

1
Unusually high alkaline phosphatase due to intestinal isoenzyme in a healthy adult.健康成年人因肠道同工酶导致碱性磷酸酶异常升高。
Clin Chem Lab Med. 2005;43(11):1274-5. doi: 10.1515/CCLM.2005.218.
2
[Alkaline phosphatase activity in blood group B or O secretors is fluctuated by the dinner intake of previous night].B型或O型分泌型血型者血液中的碱性磷酸酶活性会因前一晚晚餐的摄入量而波动。
Rinsho Byori. 2013 Apr;61(4):307-12.
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The effect of different buffers and amounts of intestinal alkaline phosphatase isoforms on total alkaline phosphatase activity.不同缓冲液及肠碱性磷酸酶同工酶量对总碱性磷酸酶活性的影响。
Clin Chim Acta. 2002 May 7;319(1):49-55. doi: 10.1016/s0009-8981(02)00008-6.
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[Proceedings: Intestinal alkaline phosphatase isoenzyme in chronic liver disease].[会议论文:慢性肝病中的肠碱性磷酸酶同工酶]
Vutr Boles. 1976;15(1):75-7.
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[Relationship between the effects of a high-fat meal and blood group in determination of alkaline phosphatase activity].[高脂肪餐的影响与血型在碱性磷酸酶活性测定中的关系]
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Intestinal alkaline phosphatase and the ABO blood group system--a new aspect.肠道碱性磷酸酶与ABO血型系统——一个新视角。
Clin Chim Acta. 1980 Nov 20;108(1):81-7. doi: 10.1016/0009-8981(80)90295-8.
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Interpretation and clinical significance of alkaline phosphatase isoenzyme patterns.碱性磷酸酶同工酶谱的解读及临床意义
Crit Rev Clin Lab Sci. 1994;31(3):197-293. doi: 10.3109/10408369409084677.
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[Incidence and characteristics of intestinal hyperphosphatasemia in healthy subjects].[健康受试者肠道高磷酸酶血症的发病率及特征]
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[Estimation of blood-group-dependent hyperphosphatasemia in healthy subjects by agarose gel electrophoresis].[通过琼脂糖凝胶电泳评估健康受试者中血型依赖性高磷酸酶血症]
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[Importance of the intestinal alkaline phosphatase isoenzyme determination in viral hepatitis].[肠道碱性磷酸酶同工酶测定在病毒性肝炎中的重要性]
Vrach Delo. 1979 Dec(12):96-8.

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