Cho Sung R, Lim Young A, Lee Wee G
Department of Laboratory Medicine, Ajou University School of Medicine, Suwon, Republic of Korea.
Clin Chem Lab Med. 2005;43(11):1274-5. doi: 10.1515/CCLM.2005.218.
Intestinal alkaline phosphatase (ALP) is more prevalent in individuals of blood group O or B, and increases after a meal, especially on a high-fat diet. We did not realize that clinicians could underestimate the importance of fasting for ALP measurement until one healthy adult showed a huge difference in ALP levels before and after a meal. We report a case of transient hyperphosphatasemia resulting in unnecessary workup due to intestinal ALP in a healthy adult of blood group O.
肠道碱性磷酸酶(ALP)在O型或B型血的个体中更为普遍,并且在进食后会升高,尤其是在高脂饮食后。直到一名健康成年人在进食前后的ALP水平出现巨大差异,我们才意识到临床医生可能低估了空腹对ALP测量的重要性。我们报告了一例因肠道ALP导致的短暂性高磷酸酶血症病例,该病例发生在一名健康的O型血成年人身上,导致了不必要的检查。