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肥胖是眼部疾病的一个风险因素。

[Obesity is a risk factor for eye diseases].

作者信息

Habot-Wilner Zohar, Belkin Michael

机构信息

Goldschleger Eye Institute, Sheba Medical Center, Tel Aviv University, Tel Hashomer, Israel.

出版信息

Harefuah. 2005 Nov;144(11):805-9, 821.

PMID:16358658
Abstract

Obesity is the most prevalent metabolic disease in developed countries and its prevalence rates worldwide are increasing rapidly. The disease is associated with a considerably enhanced morbidity in many body systems as well as mortality. This article reviews the effects of obesity on the four major blinding eye diseases: age-related macular degeneration, diabetic retinopathy, cataract and glaucoma, and shows that obesity is a significant risk factor for these diseases and hence to blindness.

摘要

肥胖是发达国家最普遍的代谢性疾病,其在全球的患病率正在迅速上升。这种疾病与许多身体系统的发病率显著增加以及死亡率相关。本文综述了肥胖对四种主要致盲眼病的影响:年龄相关性黄斑变性、糖尿病视网膜病变、白内障和青光眼,并表明肥胖是这些疾病以及失明的一个重要危险因素。

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Obesity-induced metabolic disturbance drives oxidative stress and complement activation in the retinal environment.
肥胖诱导的代谢紊乱在视网膜环境中引发氧化应激和补体激活。
Mol Vis. 2018 Mar 7;24:201-217. eCollection 2018.