Woźniak M Artur, Dobrzyński Paweł, Gutowska Agnieszka
Klinika Otolaryngologii CSK MSWiA, Warszawie.
Pol Merkur Lekarski. 2005 Sep;19(111):440-1.
In this article the authors describe a rare case of olfactory neuroblastoma in a 55-year-old woman surgically treated because of nasal polyposis. Three years earlier she had been operated for nasal polyposis on the same side in another ENT department. Unfortunately these lesions may had not been evaluated histologically. One of the surgically removed polyps was atypical. In histopathological examination it was confirmed to be olfactory neuroblastoma. CT scan revealed abnormal thickness of the mucosa in the upper part of the nose and ethmoidal sinuses on the right side. The tumor was classified as stage B in Kadish classification of olfactory neuroblastoma. The histopathologic diagnosis and CT scan made after the surgery resulted in necessity of further oncological treatment. The olfactory neuroblastoma is rare, difficult to diagnose, malignant, slowly growing tumor arising from the olfactory epithelium in the upper nasal cavity. The treatment includes surgery, radiotherapy and chemotherapy. Another objective of this paper is to point out that histopathological examination is crucial in each surgically removed tissue.
在本文中,作者描述了一例罕见的嗅神经母细胞瘤病例,患者为一名55岁女性,因鼻息肉接受手术治疗。三年前,她曾在另一家耳鼻喉科因同侧鼻息肉接受手术。遗憾的是,这些病变可能未进行组织学评估。手术切除的息肉中有一个是非典型的。组织病理学检查证实为嗅神经母细胞瘤。CT扫描显示右侧鼻腔上部和筛窦黏膜厚度异常。该肿瘤在嗅神经母细胞瘤的Kadish分类中被归为B期。手术后进行的组织病理学诊断和CT扫描表明有必要进行进一步的肿瘤治疗。嗅神经母细胞瘤是一种罕见、难以诊断、恶性、生长缓慢的肿瘤,起源于鼻腔上部的嗅上皮。治疗方法包括手术、放疗和化疗。本文的另一个目的是指出组织病理学检查对于每一个手术切除的组织都至关重要。