Nishiike Suetaka, Nagai Miki, Nakagawa Aya, Konishi Masaki, Sakata Yoshiharu, Aihara Teruhito, Harada Tamotsu
Department of Otolaryngology, Kawasaki Medical School, Kurashiki, Okayama, Japan.
J Laryngol Otol. 2006 Feb;120(2):151-3. doi: 10.1017/S0022215105005955. Epub 2005 Nov 25.
Laryngeal tuberculosis is a rare entity and the disease related to laryngeal cancer is extremely rare. We describe a case of laryngeal tuberculosis in a 74-year-old man with a history of radiotherapy for laryngeal carcinoma four months earlier. Laryngoscopy demonstrated a white mass on the right vocal fold at the site carcinoma had previously occupied. Recurrence of the cancer was suspected, but the biopsy result showed histological features of tuberculosis. We discuss the derangement of the host's mucosal barrier by the malignancy as a contributing factor in secondary tuberculous infection. Tubercular bacilli may be reactivated due to the immunosuppression associated with the therapy.
喉结核是一种罕见疾病,而与喉癌相关的疾病极为罕见。我们描述了一例74岁男性喉结核病例,该患者四个月前有喉癌放疗史。喉镜检查显示在先前癌灶所在的右侧声带处有一个白色肿物。怀疑为癌症复发,但活检结果显示为结核的组织学特征。我们讨论了恶性肿瘤对宿主黏膜屏障的破坏作为继发性结核感染的一个促成因素。结核杆菌可能由于与治疗相关的免疫抑制而被重新激活。