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关于细胞中对渗透压无反应的水室。

On the osmotically unresponsive water compartment in cells.

作者信息

Fullerton Gary D, Kanal Kalpana M, Cameron Ivan L

机构信息

Department of Radiology, The University of Texas Health Science Center at San Antonio, Floyd Curl Drive, San Antonio, TX, USA.

出版信息

Cell Biol Int. 2006 Jan;30(1):74-7. doi: 10.1016/j.cellbi.2005.09.007. Epub 2005 Dec 15.

DOI:10.1016/j.cellbi.2005.09.007
PMID:16360324
Abstract

Differences in colligative properties (freezing point, boiling point, vapor pressure and osmotic behavior) between water in living cells and pure bulk water were investigated by re-evaluating reports of the osmotic behavior of mammalian cells. In five different animal cells, osmotically unresponsive water (OUW) values ranged from 1.1 to 2.2 g per g dry mass. Detailed analysis of human red blood cell (RBC) data indicates a major role for hemoglobin OUW-values, aggregation and packing in cell volume regulation that can be explained for the first time in relevant molecular terms.

摘要

通过重新评估哺乳动物细胞渗透行为的报告,研究了活细胞中的水与纯大量水之间在依数性(冰点、沸点、蒸气压和渗透行为)方面的差异。在五种不同的动物细胞中,每克干质量的非渗透响应水(OUW)值在1.1至2.2克之间。对人类红细胞(RBC)数据的详细分析表明,血红蛋白的OUW值、聚集和堆积在细胞体积调节中起主要作用,这首次可以用相关分子术语来解释。

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