Galli Jacopo, Parrilla Claudio, Fiorita Antonella, Marchese Maria Raffaella, Paludetti Gaetano
Institute of Otolaryngology, Catholic University of Sacred Heart, Rome, Italy.
Otolaryngol Head Neck Surg. 2005 Dec;133(6):923-8. doi: 10.1016/j.otohns.2005.04.007.
To assess clinical safety and efficacy of the erbium: yttrium-aluminum-garnet (Er:YAG) laser in the stapes surgery; to define and optimize parameters that render the procedure safe for the inner ear.
Retrospective study.
A microscope-integrated Er:YAG laser stapedotomy was performed on 29 patients and a conventional stapedotomy on 41 patients. An early (within 1 to 3 days after stapes surgery) and late (at least 6 weeks) pure-tone bone-conduction threshold audiogram was obtained.
No statistically significant differences were found by Student's t test over all measured frequencies between pre- and postoperative bone-conduction thresholds in each group. There was no statistically significant difference for all frequencies between early (3 days) and late postoperative mean bone-conduction thresholds.
The results of our preliminary clinical study showed that erbium laser poses no risk to inner ear function. However, the lack of standardization obliges further investigation to establish safe clinical parameters of the Er:YAG laser.
评估铒：钇铝石榴石（Er:YAG）激光在镫骨手术中的临床安全性和有效性；确定并优化使该手术对内耳安全的参数。
回顾性研究。
对29例患者实施显微镜集成式Er:YAG激光镫骨足板切除术，对41例患者实施传统镫骨足板切除术。获取早期（镫骨手术后1至3天内）和晚期（至少6周后）的纯音骨导阈值听力图。
每组术前和术后骨导阈值在所有测量频率上经学生t检验未发现统计学显著差异。术后早期（3天）和晚期平均骨导阈值在所有频率上均无统计学显著差异。
我们的初步临床研究结果表明，铒激光对内耳功能无风险。然而，由于缺乏标准化，有必要进一步研究以确定Er:YAG激光的安全临床参数。
