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肝动脉瘤和脾动脉瘤

Hepatic and splenic artery aneurysms.

作者信息

Berceli Scott A

机构信息

Department of Surgery, University of Florida, Gainesville, 32607, USA.

出版信息

Semin Vasc Surg. 2005 Dec;18(4):196-201. doi: 10.1053/j.semvascsurg.2005.09.005.

DOI:10.1053/j.semvascsurg.2005.09.005
PMID:16360576
Abstract

Accounting for 80% of all visceral artery aneurysms, splenic and hepatic artery lesions are rare but potentially life threatening. Although their natural history has not been well-defined, the high mortality associated with emergent repair suggests an aggressive approach is indicated. While repair is clearly mandated in patients with a symptomatic aneurysm or contained rupture, the following asymptomatic lesions also warrant intervention: (1) splenic artery aneurysms in patients with the potential to become pregnant or requiring liver transplantation, (2) hepatic aneurysms in patients with polyarteritis nodosa or fibromuscular dysplasia, (3) splenic or hepatic artery aneurysms greater than 2.0 cm in diameter, and (4) splenic or hepatic pseudoaneurysms. Although open surgical interventions have traditionally been the mainstay of therapy, endovascular techniques have increasingly been applied to this problem. Dictated predominately by the need to maintain distal end-organ perfusion, potential therapies include open surgical ligation, autogenous reconstruction, endovascular coil embolization, or percutaneous endograft placement. While offering alternative approaches, endovascular techniques have not dramatically altered the risk-to-benefit ratio in asymptomatic lesions, and both open and percutaneous approaches present viable options for elective repair. Although explored in only a limited number of patients, the application of endovascular techniques to the symptomatic patient offers the greatest potential for significant improvements in morbidity and mortality.

摘要

脾动脉和肝动脉病变占所有内脏动脉瘤的80%,虽然罕见,但有潜在生命危险。尽管其自然病程尚未明确,但急诊修复相关的高死亡率提示应采取积极的治疗方法。对于有症状的动脉瘤或局限性破裂的患者,修复显然是必要的,以下无症状病变也需要干预:(1)有可能怀孕或需要肝移植的患者的脾动脉瘤;(2)患有结节性多动脉炎或纤维肌发育异常的患者的肝动脉瘤;(3)直径大于2.0 cm的脾动脉或肝动脉瘤;(4)脾或肝假性动脉瘤。虽然传统上开放手术干预一直是主要治疗方法,但血管内技术越来越多地应用于这个问题。主要出于维持远端终末器官灌注的需要,潜在的治疗方法包括开放手术结扎、自体血管重建、血管内弹簧圈栓塞或经皮腔内血管移植物置入。血管内技术虽然提供了替代方法,但并未显著改变无症状病变的风险效益比,开放手术和经皮手术方法都是选择性修复的可行选择。虽然仅在少数患者中进行了探索,但将血管内技术应用于有症状的患者,在降低发病率和死亡率方面具有最大的潜力。

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