Tan G S W, Hoh S-T, Husain R, Gazzard G, Oen F T S, Seah S K L, Aung T
Singapore National Eye Centre, Singapore 168751.
Br J Ophthalmol. 2006 Jan;90(1):14-6. doi: 10.1136/bjo.2005.077115.
BACKGROUND/AIM: Primary lens extraction has been advocated for acute primary angle closure (APAC), but it is not known if this is warranted in all cases. The aim of this study was to investigate the visual acuity (VA) of APAC eyes shortly after resolution of the acute episode in order to assess the appropriateness of performing such surgery in this condition.
This was a prospective observational case series. As part of a randomised controlled trial comparing phacoemulsification and laser iridotomy, 135 consecutive APAC subjects over a 2 year period underwent subjective refraction and measurement of Snellen VA once the acute episode had resolved with reduction of intraocular pressure (IOP) and improved corneal clarity.
Subjects were predominantly Chinese (95.6%) and female (79.3%), with a mean age of 63.6 (SD 9.6) years. When assessed 1.7 (2.7) days after presentation, the majority of APAC cases (50.4%) had good VA (6/12 or better), with more than a quarter of cases having VA of 6/7.5 or better. Poor VA was associated with duration of symptoms (p = 0.04, OR = 4.1, 95% CI 1.1 to 15.7) and time taken to resolution of APAC (p = 0.04, OR = 2.2, 95% CI 1.02 to 4.6), but not with sex (p = 0.31), age (p = 0.26), duration from presentation to measurement of visual acuity (p = 0.53), or presenting IOP (p = 0.73).
Within days after APAC, more than half of APAC affected eyes had good VA (6/12 or better). The role of lens extraction in the management of APAC warrants further debate, especially for eyes with good VA.
背景/目的:对于急性原发性闭角型青光眼(APAC),有人主张进行原发性晶状体摘除术,但尚不清楚是否所有病例都有必要进行该手术。本研究的目的是调查APAC患者急性发作缓解后不久的视力(VA),以评估在这种情况下进行此类手术的合理性。
这是一项前瞻性观察性病例系列研究。作为一项比较超声乳化术和激光虹膜切开术的随机对照试验的一部分,在2年期间,135例连续的APAC患者在急性发作通过降低眼压(IOP)和改善角膜清晰度而得到缓解后,接受了主观验光和Snellen视力测量。
受试者主要为中国人(95.6%),女性(79.3%),平均年龄63.6(标准差9.6)岁。在就诊后1.7(2.7)天进行评估时,大多数APAC病例(50.4%)视力良好(6/12或更好),超过四分之一的病例视力为6/7.5或更好。视力差与症状持续时间(p = 0.04,OR = 4.1,95%CI 1.1至15.7)和APAC缓解所需时间(p = 0.04,OR = 2.2,95%CI 1.02至4.6)相关,但与性别(p = 0.31)、年龄(p = 0.26)、就诊至测量视力的时间(p = 0.53)或就诊时的眼压(p = 0.73)无关。
APAC发作后的数天内,超过一半的APAC受累眼视力良好(6/12或更好)。晶状体摘除术在APAC治疗中的作用值得进一步探讨,尤其是对于视力良好的眼睛。