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白内障超声乳化吸除联合房角粘连分离术治疗急性闭角型青光眼后失控的慢性闭角型青光眼

Combined phacoemulsification and goniosynechialysis for uncontrolled chronic angle-closure glaucoma after acute angle-closure glaucoma.

作者信息

Teekhasaenee C, Ritch R

机构信息

Department of Ophthalmology, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

出版信息

Ophthalmology. 1999 Apr;106(4):669-74; discussion 674-5. doi: 10.1016/S0161-6420(99)90149-5.

DOI:10.1016/S0161-6420(99)90149-5
PMID:10201585
Abstract

OBJECTIVE

To evaluate combined phacoemulsification, posterior chamber intraocular lens (PCIOL) implantation, and goniosynechialysis (phaco-GSL) prospectively in eyes with more than 180 degrees of peripheral anterior synechiae (PAS) and uncontrolled intraocular pressure (IOP) when performed within 6 months of an attack of acute angle-closure glaucoma (ACG).

DESIGN

Prospective, noncontrolled clinical trial.

PARTICIPANTS

Patients who had presented with acute ACG and had persistently uncontrolled IOP despite successful laser iridotomy for pupillary block and argon laser peripheral iridoplasty for continued appositional closure after iridotomy.

INTERVENTION

After the completion of phacoemulsification and posterior chamber lens implantation, goniosynechialysis was performed in 52 eyes of 48 patients.

MAIN OUTCOME MEASURES

Postoperative visual acuity, IOP, extent of PAS, and number of medications, if any, required for IOP control.

RESULTS

Intraocular pressure was less than 20 mmHg in 47 eyes (90.4%) without medications; 4 were controlled with medications and 1 required filtration. Mean extent of PAS was reduced from 310 degrees to 60 degrees. Peripheral anterior synechiae formation or IOP elevation did not recur after 3 months after surgery up to 6 years. Eight patients achieved 20/20 visual acuity, while 44 patients had less than 20/20 visual acuity. No patient had worse visual acuity after surgery compared to before surgery.

CONCLUSION

Phaco-GSL and PCIOL implantation is effective in reducing PAS and IOP and improving visual acuity in eyes with persistent chronic ACG when performed within 6 months after treatment for acute ACG.

摘要

目的

对在急性闭角型青光眼(ACG)发作6个月内进行手术,周边前粘连(PAS)超过180度且眼压(IOP)控制不佳的患者,前瞻性评估白内障超声乳化吸除术、后房型人工晶状体(PCIOL)植入术和房角粘连分离术(phaco-GSL)联合应用的效果。

设计

前瞻性、非对照临床试验。

研究对象

出现急性ACG,尽管已成功进行瞳孔阻滞激光虹膜切开术及氩激光周边虹膜成形术以防止虹膜切开术后持续性房角关闭,但眼压仍持续控制不佳的患者。

干预措施

48例患者的52只眼在完成白内障超声乳化吸除术及后房型人工晶状体植入术后,进行房角粘连分离术。

主要观察指标

术后视力、眼压、PAS范围以及控制眼压所需的药物数量(如有)。

结果

47只眼(90.4%)无需药物治疗眼压即低于20 mmHg;4只眼需药物控制,1只眼需行滤过手术。PAS平均范围从310度降至60度。术后3个月至6年,未见PAS形成或眼压升高复发。8例患者术后视力达到20/20,44例患者视力低于20/20。与术前相比,无患者术后视力变差。

结论

在急性ACG治疗后6个月内进行phaco-GSL及PCIOL植入术,可有效减少PAS、降低眼压并提高持续性慢性ACG患者的视力。

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